地址:北京市海淀區(qū)清河安寧莊后街12號院1號樓一層、安寧莊東路18號光華創(chuàng)業(yè)園16號樓四層 電話:4008113950 ; 4008113680 后臺管理 CRM
技術(shù)支持:興旺寶明通
一、產(chǎn)品概述:
芬蘭NeurOne EEG/ERP高精度腦電測量/事件相關(guān)電位系統(tǒng)是最新研發(fā)的創(chuàng)新型腦科學(xué)研究高端儀器設(shè)備,NeurOne認知神經(jīng)科學(xué)測量系統(tǒng)采用了世界最新的數(shù)字信號處理技術(shù)發(fā)展,目前是全世界性能最好的神經(jīng)科學(xué)測量腦電與事件相關(guān)電位系統(tǒng),并提供了更加精確與干凈的信號質(zhì)量、更高的采樣率、模塊化解決方案,在數(shù)字信號加工過程中利用最新處理手段,使其更加具有靈活性和擴展性。NeurOne是一個多功能系統(tǒng),廣泛應(yīng)用于不同的認知神經(jīng)科學(xué)、心理與行為科學(xué)以及人因工程與工效學(xué)等研究領(lǐng)域。
二、多模態(tài)腦功能研究:
NeurOne系統(tǒng)可以與fMRI功能性核磁共振、fNIRS功能性近紅外光譜腦成像或者TMS經(jīng)顱磁刺激器結(jié)合進行多模態(tài)腦功能實驗研究;NeurOne提供了專為與TMS經(jīng)顱磁刺激器一起使用的功能模塊,有特殊還原技術(shù)在短延時情況下來消除磁制品影響。先進的頭盒設(shè)計使AC交流電和DC直流電信號可單獨或同時,新的創(chuàng)新Tesla核磁腦電放大器給NeurOne帶來MRI兼容性。
NeurOne腦電超掃描系統(tǒng)每個放大器的Headbox由32個單極、6個雙極和2個high level輸入接口組成,共計40導(dǎo),每導(dǎo)的采樣率能達到40000Hz,最高可以達到80000Hz。團體超掃描腦電測試平臺每套系統(tǒng)可提供多至2-30個放大器(共計128/1200導(dǎo))的協(xié)調(diào)同步,并可選擇支持視頻同步。NeurOne系統(tǒng)最高支持1200高導(dǎo)聯(lián),并可確保所有通道的同步采集。精心設(shè)計的啟動和時間鎖定功能確保系統(tǒng)中所有通道無相位偏差。所有的通道都使用高質(zhì)量的24位A/D模擬數(shù)字芯片來處理數(shù)據(jù)。
三、多功能應(yīng)用:
●1、EEG-Hyperscanning腦電超掃描研究:
NeurOne腦電超掃描系統(tǒng)的模塊化設(shè)計可以提供多達2-30人實時同步進行腦功能超掃描測試使用系統(tǒng),并支持完全同步視頻的攝影機。使用創(chuàng)新的Brainstorm超掃描技術(shù) (Multi Syncbox),支持多達10個 NeurOne主機系統(tǒng)實時同步,允許最多30人使用30個放大器同時工作–均由一臺電腦記錄。
●2、EEG-fNIRS多模態(tài)研究: NeurOne多模態(tài)腦功能測試系統(tǒng)可以和fNIRS(高密度近紅外腦功能成像系統(tǒng))搭配使用,將EEG和fNIRS進行整合發(fā)揮二者的優(yōu)勢,EEG的時間分辨率高,但是空間分辨率低;fNIRS的時間分辨率低,實時性較差,但是空間分辨率高。為了準確、全面、實時的測量大腦在認知過程中的活動,實現(xiàn)全面、實時的腦成像方式無疑是一種更好的策略。結(jié)合EEG與fNIRS的多模態(tài)腦成像技術(shù)在認知神經(jīng)科學(xué)研究中有著很好的應(yīng)用前景,同時還可搭建多模態(tài)腦-機接口系統(tǒng)。
●3、EEG-fNIRS多模態(tài)腦機接口研究:傳統(tǒng)基于單一模態(tài)腦電(EEG)腦-機接口易受環(huán)境噪聲干擾、分類精度低等問題,在EEG腦-機接口的研究基礎(chǔ)上,引入功能近紅外光譜成像(function NearInfraredSpectroscopy,fNIRS)技術(shù),可以自行設(shè)計EEG-fNIRS多模態(tài)腦-機接口的實驗范式,研究最重要的特征提取與分類環(huán)節(jié),同時SIMULINK驅(qū)動程序可在訂單中選購,并提供BCI腦機接口應(yīng)用程序: BCI2000可免費提供給NeurOne用戶。
●4、EEG-TMS多模態(tài)研究: NeurOne多模態(tài)腦功能測試系統(tǒng)可以和TMS(經(jīng)顱磁刺激器)搭配使用。高動態(tài)輸入范圍(+/-430mV的直流電模式以及+/-86mV的交流電模式),較大的模擬帶寬(直流輸出3500HZ),讓TMS保持較低的偽影,使得分析大腦活動的潛伏期更短。此外,TMS擁有硬件弱音功能以及在線偽影消除的軟件功能。此外我們增加了EEG采樣同步觸發(fā)新功能。觸發(fā)器由刺激系統(tǒng)軟件發(fā)出(ErgoLAB刺激編譯軟件、Presentation軟件, Superlab軟件, E-Prime軟件),這些觸發(fā)信號能夠通過NeurOne主控器傳到TMS設(shè)備上。NeurOne可以在持續(xù)的EEG采樣信號中發(fā)出觸發(fā)脈沖,產(chǎn)生更精確的TMS,減少偽影,更容易進行偽影去除。
NeurOne結(jié)合TMS案例應(yīng)用:http://m.qilumeiwen.com/newsShow_88.html
●5、EEG-fMRI多模態(tài)研究: NeurOne Tesla多模態(tài)腦功能測試系統(tǒng)使得同時測量MRI和EEG成為可能。利用NeurOne SyncboxEEG所獲得的數(shù)據(jù)和MRI掃描是同步的(例如4或10MHz)。高動態(tài)輸入范圍(+/- 430 mV的直流電模式和 +/-86 mV的交流電模式)結(jié)合模擬帶寬(直流輸出3500 Hz) ,使利用高梯度力度獲得精確信號毫無風(fēng)險。
四、應(yīng)用領(lǐng)域:
EEG/EP測量
ERP研究
EEG +TMS結(jié)合多模態(tài)腦功能研究
EEG +fMRI結(jié)合多模態(tài)腦功能研究
多通道EMG肌電圖研究
群組超掃描研究(多達4人4視頻攝像機完全同步)
其他神經(jīng)科學(xué)的測量
其他心理測量
五、 NeurOne放大器參數(shù):
放大器采樣率:512導(dǎo)同時采集,每導(dǎo)可達20,000 Hz ;20000 HZ/每通道(512導(dǎo)單人/或最大30人團體1200導(dǎo))
最大通道數(shù):所有導(dǎo)聯(lián)均同步采集信號,最大支持1200高導(dǎo)聯(lián),
腦電超掃描技術(shù):支持Hyperscanning最多支持30人同步采集團體腦電數(shù)據(jù);
多模態(tài)腦功能測試技術(shù):支持EEG-TMS,EEG-fNIRS,EEG-fMRI等研究技術(shù)方案
A/D Resolution:24 Bit
輸入阻抗:>1 GOhms
共模抑制比(CMRR): Typically 106 dB
帶寬(Bandwidth): Max. 0 ~ 3500Hz
低通濾波:DC (10000Hz) ; -3 dB(7000 Hz)
高通濾波: -3 dB(0.16 Hz)
輸入噪聲(InputNoise):(DC Mode):<0.8uV RMS (0-200 Hz),<2.0uV RMS(DC-3500 Hz) ;
輸入范圍(Full Scale Input Range)(DC Mode):± 430 mV
系統(tǒng)增益(System Gain)(DC Mode):10
靈敏度(Sensitivity)(DC Mode): 51 nV/bit
噪聲(Noise)(AC Mode):<0.6 μV RMS (0.16-200 Hz), < 1.5 μV RMS (0.16-3500 Hz)
輸入范圍(Full Scale Input Range)(AC Mode):± 4.3 mV
系統(tǒng)增益(System Gain)(AC Mode): 50
靈敏度(Sensitivity)(AC Mode): 0.51 nV/bit
數(shù)字化(TTL)輸入: 8 Bit非隔離輸入觸發(fā),2個隔離輸入/輸出線2 isolated trigger in/out lines, 8 bit unisolated trigger in
High Level 輸入范圍: ± 5V or ± 10V (with isolated analog adapter, settable)
阻抗: 1 kΩ to 50 kΩ
Headbox 體積(H x W x D): 20 x 7 x 16 (40 channels),
Headbox 重量: 0.680 kg
Main unit體積(H x W x D):33×12×27 cm,
Main unit重量:3.6
安全規(guī)范:EN 60601-1,EN 60601-1-1,EN 60601-1-2,EN60601-1-4,EN60601-2-26
NeurOne用戶請注意:
注意 – 僅用于科研,不用于診斷過程,設(shè)備可用于非臨床實驗研究。
PUBLICATIONS USING NEURONE EEG/ERP ORNEURONE TESLA :
1. A platform for realtime processing of biosignalsfor monitoring purposes. PITKÄNEN,PAAVO. Master of Science Thesis. Tampere University of Technology. May 2012. InFinnish
2. A New Platform for Realtime BCI Applications. Paavo Pitkänen1,2,Jukka Kinnunen2, Tarmo Lipping1 (IEEE,Senior Member). 1 Tampere University Of Technology, 2 Mega Electronics Ltd. Poster at Berlin BCI meeting 2012
3. Visual ERP P3 amplitude and latency in standaloneand embedded visual processing task. Conf Proc IEEE Eng Med Biol Soc. 2011;2011:781-4.doi: 10.1109/IEMBS.2011.6090179. Korpela J, Huotilainen M. Brain Work ResearchCentre, Finnish Institute of Occupational Health, Helsinki, Finland. jussi.korpela@ttl.fi
4. The effect of automatic blink correction onauditory evoked potentials. Korpela,J. ; Brain Work Res. Centre, Finnish Inst. of Occupational Health, Helsinki,Finland ; Vigario, R. ; Huotilainen, M. 10.1109/EMBC.2012.6346009
5. Breakfast high in whey protein or carbohydratesimproves coping with workload in healthy subjects. Nora Sihvola a1, Riitta Korpela a1, Andreas Henelius a2, Anu Holm a2 a3,Minna Huotilainen a2, Kiti Müller a2,Tuija Poussa a4, Kati Pettersson a2,Anu Turpeinen a5 and Katri Peuhkuri a1 c1.a1 Institute of Biomedicine, Medical NutritionPhysiology, Pharmacology, University of Helsinki, PO Box 63, HelsinkiFIN-00014, Finland. a2 Finnish Institute of Occupational Health,Brain and Technology Team, Topeliuksenkatu 41 aA, Helsinki FIN-00250, Finland. a3 Department of Clinical Neurophysiology, Hospital District of Satakunta,Sairaalantie 3, Pori FIN-28500, Finland a4 Stat-Consulting,Vahverokatu 6, Nokia FIN-37130, Finland a5 ValioLimited, PO Box 30, VALIO, Helsinki FIN-00039, Finland British Journal ofNutrition, 2013
6. Pilot Study ofAcupuncture Point Laterality: Evidence from Heart Rate Variability. Guangjun Wang, Yuying Tian, ShuyongJia,Wenting Zhou, and Weibo Zhang.
Institute ofAcupuncture and Moxibustion, China Academy of Chinese Medical Sciences, 16Dongzhimennei, Nanxiaojie, Dongchen District, Beijing 100700, China Evidence-BasedComplementary and Alternative Medicine. Volume 2013 (2013), Article ID 476064,7 pages http://www.hindawi.com/journals/ecam/aip/476064/
7. Algorithm forautomatic analysis of electro-oculographic data.
Kati Pettersson1*, Sharman Jagadeesan1, Kristian Lukander1,Andreas Henelius1, Edward Hæggström2 andKiti Müller1
1Brain Work Research Center, FinnishInstitute of Occupational Health, Topeliuksenkatu 41aA, Helsinki 00250,Finland.
2Electronics Research Laboratory, Departmentof Physics, University of Helsinki, P. O. Box 64, Gustaf Hällströmin katu 2,Helsinki FIN-00014, Finland.
BioMedicalEngineering OnLine 2013 12:110.
8. Brain-statedependent brain stimulation: Real-time EEG alpha band analysis using slidingwindow FFT phase progression extrapolation to trigger an alpha phase locked TMSpulse with 1 millisecond accuracy.
Christoph Zrenner,Johannes Tünnerhoff , Carl Zipser, Florian Müller-Dahlhaus , Ulf Ziemann
Center forNeurology, Tübingen University, Hoppe-Seyler-Str. 3, 72076 Tübingen, Germany
BrainStimulation: Basic, Translational, and Clinical Research in Neuromodulation:Volume 8, Issue 2, A1-A10, 169-438
9. Behavioral andelectrophysiological evidence for fast emergence of visual consciousness.
Henry Railo1,2,3,*,Antti Revonsuo1,2,3,4 and Mika Koivisto1,2,3
1Department of Psychology, University ofTurku, 20014, Finland; 2Centre for Cognitive Neuroscience, University of Turku, 20014, Finland;3Brain and Mind Centre, University of Turku,20014, Finland; 4School of Bioscience, University of Skövde,SE-54128, Sweden
Neuroscience ofConsciousness, 2015, 1–12
10. Fastdetermination of MMN and P3a responses to linguistically and emotionallyrelevant changes in pseudoword stimuli
Satu Pakarinen,Laura Sokka, Marianne Leinikka, Andreas Henelius, Jussi Korpela,Minna
Huotilainen
Finnish Institute ofOccupational Health, Helsinki, Finland
NeuroscienceLetters 577 (2014) 28–33
11. Alterationsin attention capture to auditory emotional stimuli in job burnout: Anevent-related potential study
Laura Sokka a, Minna Huotilainen a, Marianne Leinikka a, Jussi Korpela a, Andreas Henelius a,Claude Alain b,c, Kiti Müller a,Satu Pakarinena
a Finnish Institute of Occupational Health,Topeliuksenkatu 41 a A, 00250 Helsinki, Finland
b Rotman Research Institute, Baycrest Centrefor Geriatric Care, 3560 Bathurst Street, Toronto, Ontario, Canada M6A 2E1
c Department of Psychology, University ofToronto, Toronto, Ontario, Canada
InternationalJournal of Psychophysiology 94 (2014) 427–436
12. Brain-statedependent non-invasive brain stimulation using closed-loop real-time EEG signalanalysis to trigger a TMS pulse with millisecond accuracy
C. Zrenner, J.Tünnerhoff, C. Zipser, F. Müller-Dahlhaus, U. Ziemann
University ofTübingen, Center of Neurology, Tübingen, Germany
SocietyProceedings / Clinical Neurophysiology 126 (2015) e63–e170
13. BilateralHegu Acupoints Have the Same Effect on the Heart Rate Variability of theHealthy Subjects
Wang Guangjun, TianYuying, Jia Shuyong, ZhouWenting, and ZhangWeibo
Institute ofAcupuncture and Moxibustion, China Academy of Chinese Medical Sciences,
Beijing 100700,China
Hindawi PublishingCorporation
Evidence-BasedComplementary and Alternative Medicine
Volume 2014, ArticleID 106940, 5 pages (http://dx.doi.org/10.1155/2014/106940)
14. AcupunctureRegulates the Heart Rate Variability
Guangjun Wang,Yuying Tian, Shuyong Jia, Wenting Zhou, Weibo Zhang
Institute ofAcupuncture and Moxibustion, China Academy of Chinese Medical Sciences,
Beijing, China
J AcupunctMeridian Stud 2015;8(2):94-98
15. Closed-LoopNeuroscience and Non-Invasive Brain Stimulation: A Tale of Two Loops
Christoph Zrenner,Paolo Belardinelli, Florian Müller-Dahlhaus and Ulf Ziemann
Brain Network andPlasticity Laboratory, Department of Neurology and Stroke and Hertie-Institutefor Clinical Brain Research, University of Tübingen, Tübingen, Germany
Frontiers inCellular Neuroscience, April 2016, Volume 10, Article 92
16. Physiologicalprocesses non-linearly affect electrophysiological recordings duringtranscranial electric stimulation
Noury, N., et al.,NeuroImage (2016), http://dx.doi.org/10.1016/j.neuroimage.2016.03.065
17. Job burnout is associated with dysfunctions inbrain mechanisms ofvoluntary and involuntary attention Laura Sokka, Marianne Leinikka, JussiKorpela, Andreas Henelius, Lauri Ahonen,Claude Alain, Kimmo Alho, MinnaHuotilainen, http://dx.doi.org/10.1016/j.biopsycho.2016.02.010
18. Shifting ofattentional set is inadequate in severe burnout: Evidence from an event-relatedpotential study
Laura Sokka, MarianneLeinikka, Jussi Korpela, Andreas Henelius, Jani Lukander, Satu Pakarinen, KimmoAlho, Minna Huotilainen. PII: S0167-8760(16)30853-4 DOI: doi:10.1016/j.ijpsycho.2016.12.004
放大器采樣率:512導(dǎo)同時采集,每導(dǎo)可達20,000 Hz ;20000 HZ/每通道(512導(dǎo)單人/或最大30人團體1200導(dǎo))
最大通道數(shù):所有導(dǎo)聯(lián)均同步采集信號,最大支持1200高導(dǎo)聯(lián),
腦電超掃描技術(shù):支持Hyperscanning最多支持30人同步采集團體腦電數(shù)據(jù);
多模態(tài)腦功能測試技術(shù):支持EEG-TMS,EEG-fNIRS,EEG-fMRI等研究技術(shù)方案
A/D Resolution:24 Bit
輸入阻抗:>1 GOhms
共模抑制比(CMRR): Typically 106 dB
帶寬(Bandwidth): Max. 0 ~ 3500Hz
低通濾波:DC (10000Hz) ; -3 dB(7000 Hz)
高通濾波: -3 dB(0.16 Hz)
輸入噪聲(InputNoise):(DC Mode):<0.8uV RMS (0-200 Hz),<2.0uV RMS(DC-3500 Hz) ;
輸入范圍(Full Scale Input Range)(DC Mode):± 430 mV
系統(tǒng)增益(System Gain)(DC Mode):10
靈敏度(Sensitivity)(DC Mode): 51 nV/bit
噪聲(Noise)(AC Mode):<0.6 μV RMS (0.16-200 Hz), < 1.5 μV RMS (0.16-3500 Hz)
輸入范圍(Full Scale Input Range)(AC Mode):± 4.3 mV
系統(tǒng)增益(System Gain)(AC Mode): 50
靈敏度(Sensitivity)(AC Mode): 0.51 nV/bit
數(shù)字化(TTL)輸入: 8 Bit非隔離輸入觸發(fā),2個隔離輸入/輸出線2 isolated trigger in/out lines, 8 bit unisolated trigger in
High Level 輸入范圍: ± 5V or ± 10V (with isolated analog adapter, settable)
阻抗: 1 kΩ to 50 kΩ
Headbox 體積(H x W x D): 20 x 7 x 16 (40 channels),
Headbox 重量: 0.680 kg
Main unit體積(H x W x D):33×12×27 cm,
Main unit重量:3.6
安全規(guī)范:EN 60601-1,EN 60601-1-1,EN 60601-1-2,EN60601-1-4,EN60601-2-26
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介紹 參數(shù)津發(fā)科技研發(fā)了基于云架構(gòu)的“以人為中心”的多元數(shù)據(jù)同步采集和定量化分析平臺,以測量、記錄、顯示、分析和識別人-車-路環(huán)境數(shù)據(jù)為核心。可以解決駕駛心理行為研究、車輛行駛狀態(tài)分析、主動安全駕駛與自動駕駛技術(shù)、交通道路環(huán)境數(shù)據(jù)采集等研究內(nèi)容,提供全世界范圍內(nèi)的最優(yōu)測試技術(shù)和整體解決方案。
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